This type of endothelial injury is induced by several factors, such as endotoxins, viruses, homocysteine, and cigarette smoke (Widlansky, Gokce, Keaney, & Vita, 2003). The main pathophysiological cause of CVDs is atherosclerosis, which is a chronic inflammatory reaction that begins as a response to injury of the arterial intima (Ross, 1999). Even when CVDs are not fatal, they often result in permanent damage to critical organs, which in turn causes activity restriction, nursing care, and reduced life expectancy. Unsalted tomato juice intake improved systolic and diastolic BP and serum LDL‐C level in local Japanese residents at risk of cardiovascular conditions.Ĭardiovascular diseases (CVDs) are the biggest causes of mortality worldwide, and according to the World Health Organization (WHO), they were responsible for 15.2 million global deaths (26.7%) in 2016 (retrieved from ). No significant difference in lifestyle was found before and after the study. These beneficial effects were not different between sexes and among the different age groups. Further, the serum low‐density lipoprotein cholesterol (LDL‐C) level in 125 participants with untreated dyslipidemia significantly decreased (155.0 ± 23.2–149.9 ± 25.0 mg/dl, p = 0.005, paired t test). The average ages of the 184 male and 297 female participants were 56.3 ± 13.3 (mean ± SD) and 58.4 ± 11.7 years, respectively. Of the study participants, 260 participated in a detailed study of their lifestyle factors. Participants were screened for cardiovascular risk markers, such as blood pressure (BP), serum lipid profile, and glucose tolerance, before and after the study period. Throughout the year of the study, they were provided with as much unsalted tomato juice as they wanted. Four hundred and eighty‐one local residents in Kuriyama, Japan, were enrolled in this study. Retrieved February 16, 2022.The aim of this study was to investigate the effects of unsalted tomato juice intake on cardiovascular risk markers in local Japanese residents.
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